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Will Smith nei panni del medico che con la sua scoperta fece tremare una delle organizzazioni più potenti del mondo. Un battaglia indimenticabile tratta da una storia vera. Il film racconta la storia di Bennet Omalu, il neuropatologo che cercò in ogni modo di portare all'attenzione pubblica una sua importante scoperta: una malattia degenerativa del cervello che colpiva i giocatori di football vittime di ripetuti colpi subiti alla testa. Durante la sua ostinata ricerca, il medico tentò di smantellare lo status quo dell'ambiente sportivo che, per interessi politici ed economici, metteva consapevolmente a repentaglio la salute degli atleti.

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